• Polyene phosphatidylcholine

  Time:2019-09-08 Hits:
  

  1. Name

  Chinese name: polyene phosphatidylcholine     English Name：Polyene Phosphatidylcholine

  2. Structural Formula

  

  Molecular formula：C₄₄H₈₂O₉PN       molecular weight：800（Average molecular weight）      CASNumber：8002-43-5

  3. Function and Use

  Polyene phosphatidylcholine is refined from phospholipids extracted from plants. Its main active ingredient is 1,2-dilinoleoyl phosphatidylcholine. Polyene phosphatidylcholine has the same chemical structure as important endogenous phospholipids and is superior to the latter in function. The endogenous phospholipids of human body can be replaced, combined and entered into the membrane components. The significance of this substitution is to increase membrane fluidity, while maintaining or promoting many membrane functions of different organs and tissues. These include: regulating the activity of membrane binding enzyme system; inhibiting the content and activity of cytochrome P4502E1 (CYP2E1); enhancing catalase activity, superoxide dismutase (SOD) activity and glutathione reductase activity.

  Leich et al. studied the effects of dilinoleyl phosphatidylcholine, interferon and placebo on hepatitis B and C, and concluded that dilinoleyl phosphatidylcholine can reduce the level of alanine aminotransferase (ALT) in blood. The combination of dilinoleyl phosphatidylcholine and interferon has a good effect in the treatment of hepatitis C without side effects.

  Indications: Indications for various types of liver diseases, such as hepatitis, chronic hepatitis, hepatic necrosis, cirrhosis, hepatic coma (including precursor hepatic coma). Fatty liver (also seen in diabetic patients). Bile obstruction. Poisoning. Prevention of gallstone recurrence. Treatment before and after operation, especially hepatobiliary surgery. Pregnancy poisoning, including vomiting. Psoriasis, neurodermatitis, radiation syndrome.

  4. Packaging specifications

  The inner package is a single-layer polyethylene bag plus a black plastic bag, and the outer package is a cardboard barrel, 15kg per barrel.

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